The results of numerical modeling of aerodynamics and pollution transfer in urban built-up areas are presented. The spatial microscale model includes Reynolds equations for aerodynamics prediction and "k-ε" two-parametric turbulence model. The numerical solution of the equations is based on the finite volume method. The mathematical model was verified by a set of experiments. Besides, the microscale model was compared with the field data, obtained within the TRAPOS (Optimization of Modeling Methods for Traffic Pollution in Streets) project.