The influence of weather conditions on the spreading and transformation of sulfur, nitrogen, and other minor gas constituents in the Lake Baikal region is studied through numerical simulation. The sources of the atmospheric pollutants under study are the industrial enterprises and automobile transportation of the Irkutsk-Cheremkhovo industrial region, as well as Slyudyanka, Baikalsk, Ulan-Ude, Selenginsk, and Gusinoozersk towns.